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From276US$ /night
Check-in
10Mar2026Select date
Check-out
11Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4745 Transformation Way, Jacksonville, Florida, United States, FL 32224
-
Near Shipwreck Island Water Park
Great
8.9
/10

The 4-star Hilton Jacksonville At Mayo Clinic hotel is a great place to stay in the Southpoint-Butler Blvd district, 3.8 miles from Jacksonville Beach Pier. There is a terrace bar and a swimming pool available on the premises.

Location

Adventure Landing Jacksonville Beach is a 10-minute drive from this hotel and Times Square Plaza is about 15 minutes away by car.

The closest train station to the Jacksonville hotel is Union, which is 18 miles away.

Options for cultural tourism include Beaches Museum and History Park, situated 6 km away.

Rooms

The Hilton Jacksonville At Mayo Clinic welcomes guests to 250 rooms complete with a flat-screen TV with satellite channels, as well as comforts like ironing facilities and climate control. Bathrooms feature a tub, a separate toilet, and a shower along with a hairdryer and bath sheets.

Eat & Drink

There is a terrace bar on site. The bar area includes a terrace.

Leisure & Business

This accommodation has a fitness area.

“The proximity to the Mayo Clinic is a major advantage, made even easier with shuttle service. I noted the hotel's commitment to both health and business needs, with a fitness center and business facilities on-site. It's a thoughtfully designed space that impressed me, even early into its opening.”
Hotel logo
Emily RoseEditor-in-Chief at Luxuryhotels
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Select your room type

Hilton Jacksonville At Mayo Clinic offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Queen Room Two Queen Beds Water View Hearing Accessible
2 persons
345 sq. feet 
2 King Size Beds
Water view
Shower
Heating
Queen Room Two Queen Beds Water View
2 persons
345 sq. feet 
2 King Size Beds
Water view
Shower
Heating
Queen Room Two Queen Beds Hearing Access
2 persons
345 sq. feet 
2 King Size Beds
Shower
Coffee machine
Queen Room Two Queen Beds
2 persons
345 sq. feet 
2 King Size Beds
Shower
Coffee machine
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Facilities

Hilton Jacksonville At Mayo Clinic offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Lift
  • ATM/Cash machine
  • Fireplace
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Bar/ Lounge area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Outdoor swimming pool
  • Beach umbrellas
  • Sun loungers
  • Sun terrace
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Hilton Jacksonville At Mayo Clinic Location

4745 Transformation Way, Jacksonville, Florida, United States, FL 32224
Map view
4745 Transformation Way, Jacksonville, Florida, United States, FL 32224
Explore Jacksonville
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Windsor Parke Golf Club
25 minutes' walk
An 18-hole championship golf course with lush fairways, perfect for golf enthusiasts of all skill levels.
Castaway Island Preserve
40 minutes' walk
A nature preserve featuring beautiful trails and wildlife, ideal for a peaceful day in nature.
Jacksonville Beach Golf Club
55 minutes' walk
A public golf course that offers a challenging layout along with ocean views, suitable for all players.
Shipwreck Island Water Park
45 minutes' walk
A family-friendly water park filled with fun water slides and attractions for all ages, perfect for summer outings.
Discover the local attractions near Hilton Jacksonville At Mayo Clinic
Learn about various attractions near Hilton Jacksonville At Mayo Clinic that cater to diverse interests
Great for interactive experiences: Mind Bender Escape Rooms
Ideal for enjoying nature with pets: Paws Park
Perfect for unique city tours: Go Tuk'n
Suited for learning about local history: Beaches Museum and History Park
Works well for peaceful outdoor walks: Cradle Creek Preserve
Best for scenic views and leisure: Jacksonville Beach Pier
Ideal for family-friendly entertainment: Adventure Landing Jacksonville Beach
Well suited for art enthusiasts: J. Johnson Gallery
Urban Golf
35 minutes' walk
An indoor golf simulator venue offering a modern twist on golf-ideal for both practice and leisure.
Parks and Trails
40 minutes' walk
Beautiful parks nearby with walking and biking trails, perfect for relaxation and outdoor activities.
Adventure Landing Water Park
45 minutes' walk
Thrill-seekers can enjoy various water rides and attractions at this lively water park.
Spa Days
10 minutes' drive
Local spas provide relaxing services from massages to facials-perfect after a long day.
The Capital Grille
10 minutes' drive
An upscale steakhouse known for dry-aged steaks and an extensive wine list-reservations recommended.
Mellow Mushroom
5 minutes' drive
Casual pizzeria serving creative pizzas and craft beer in a vibrant atmosphere, catering to dietary needs.
Sushi House
10 minutes' drive
Japanese sushi spot offering fresh sashimi and rolls in a cozy environment-great for sushi lovers.
Café Chophouse
5 minutes' drive
A modern American bistro with a menu featuring gourmet techniques-ideal for a fine dining experience.
Regal Beach Boulevard 18
10 minutes' drive
A popular cinema featuring the latest films; ideal for a family night out or a date night.
Mind Bender Escape Rooms
10 minutes' drive
A unique escape room experience with various themes-great for groups and an exciting challenge.
Live Music Venues
10 minutes' drive
Local venues host live music nights featuring diverse genres-perfect for enjoying Jacksonville's nightlife.
Comedy Shows
10 minutes' drive
Various venues in the area offer comedy nights for a fun evening-a good choice for all ages.
Getting around
City Centre
Jacksonville33 min  ·  13.6 mi
Airports
Jacksonville International Airport (JAX)67 min  ·  27.5 mi
St. Augustine, FL (UST)71 min  ·  29.0 mi
Train
Jacksonville Electric Authority Southside Generating Station Wharf29 min  ·  11.8 mi
Union Station35 min  ·  14.4 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Internet
Wireless internet is available in for free.
Pets
Pets are not allowed.
Number of rooms:
252

Reviews and Ratings

Feedback about Hilton Jacksonville At Mayo Clinic from previous guests about their experience.
Review score
Based on 9 verified reviews
8.6/10
Great
82%
Recommend
Pros
Large room
Good food
Accommodating staff
Front desk attention
Cons
Low water pressure
Cleaning issues
Far airport
Guest reviews
based on 49 reviews
8.9/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Hilton Jacksonville At Mayo Clinic
What are the check-in and check-out times at Hilton Jacksonville At Mayo Clinic?
Check-in is at 16:00 and check-out is at 11:00.
Is there parking available at Hilton Jacksonville At Mayo Clinic?
Public parking is available on-site for free.
What is the distance from Hilton Jacksonville At Mayo Clinic to Jacksonville International Airport?
The hotel is located 42 km from Jacksonville International Airport.
What dining options are available on-site at Hilton Jacksonville At Mayo Clinic?
The hotel features an on-site restaurant providing Full English/Irish and American breakfast options.
Are there any special amenities for families at Hilton Jacksonville At Mayo Clinic?
The hotel offers cots and a children's buffet for families.
What fitness facilities can guests use at Hilton Jacksonville At Mayo Clinic?
Guests have access to a fitness centre and an outdoor swimming pool.
What amenities are included in the rooms at Hilton Jacksonville At Mayo Clinic?
Rooms include air conditioning, a flat-screen TV, a safety deposit box, and tea/coffee making facilities.
What nearby attractions can guests visit from Hilton Jacksonville At Mayo Clinic?
Nearby attractions include Jacksonville Beach Golf Club (8 km) and Kathryn Abbey Hanna Park (17 km).
What languages do the staff speak at Hilton Jacksonville At Mayo Clinic?
The staff primarily speaks English.
Is Wi-Fi available at Hilton Jacksonville At Mayo Clinic?
Free Wi-Fi is available throughout the hotel.

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Check-in
10Mar2026Select date
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11Mar2026Select date
Rooms and Guests2 Guests, 1 Room